gene_symbol
SLAMF7
hgnc_id
HGNC:21394
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells recognize SLAMF7 on target cells, become activated, and kill via perforin/granzyme–mediated cytotoxicity (and related T cell effector pathways).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Also known as CRACC; CAR binds the extracellular domain on myeloma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06185751
disease_id_num_tar_ref
3668
drug_id_num_tar_ref
9951