gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The bispecific binds CD3 on T cells to activate them and bridge to CD22 on B cells; activated T cells kill CD22+ targets via perforin/granzyme, not CD3+ T cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell receptor-CD3 complex target (specific chain not disclosed)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06139406
disease_id_num_tar_ref
3669
drug_id_num_tar_ref
9956