gene_symbol
CD22
hgnc_id
HGNC:1643
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD3xCD22 bispecific antibody crosslinks T cells to CD22+ cells, activates TCR/CD3 signaling, and induces perforin/granzyme-mediated killing after immune synapse formation.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell lineage antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06139406
disease_id_num_tar_ref
3669
drug_id_num_tar_ref
9956