gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD19-expressing cells are recognized by CD19-directed CAR T cells, triggering T-cell cytotoxicity (perforin/granzyme and Fas-FasL pathways) leading to direct lysis/apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface B-cell antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06530849
disease_id_num_tar_ref
3705
drug_id_num_tar_ref
10032