gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD19 CAR-T cells bind CD19 on target cells and induce cytotoxicity via immunologic synapse formation with perforin/granzyme release (and death-receptor signaling), killing CD19-positive cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell lineage surface antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06462248
disease_id_num_tar_ref
3716
drug_id_num_tar_ref
10049