gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Adoptively transferred CMV-specific T cells recognize CMV peptide–HLA complexes via their native TCRs and induce apoptosis of infected cells through perforin/granzyme (and Fas–FasL) cytotoxic pathways.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
HLA-restricted TCR recognition by CD8+ and CD4+ VSTs
trial_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05664126
disease_id_num_tar_ref
3719
drug_id_num_tar_ref
10056