gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Vaccination expands neoantigen-specific CD8+ T cells that recognize the neoantigen peptide–MHC I on tumor cells and kill them via perforin/granzyme cytolysis and Fas–FasL apoptosis.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Personalized somatic mutation–derived CD8+ T-cell target; presented on HLA class I
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06631079
disease_id_num_tar_ref
3723
drug_id_num_tar_ref
10063