gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Antibody binds gp120 on Env-expressing infected cells and engages Fcγ receptors to trigger immune effector killing (ADCC by NK cells, ADCP by phagocytes; potential complement-mediated lysis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Targets gp120 on virions and Env-expressing infected cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05079451
disease_id_num_tar_ref
3796
drug_id_num_tar_ref
10257