gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR engagement of EX02 activates T cells to form an immune synapse and kill EX02-positive cells via perforin/granzyme-mediated cytolysis (and death receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface expression on AML blasts required for activity
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06642025
disease_id_num_tar_ref
320
drug_id_num_tar_ref
911