gene_symbol
FOLR1
hgnc_id
HGNC:3791
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
DC vaccine primes FRα-specific T-cell immunity; CD8+ T cells recognize FRα-derived peptides on MHC I of tumor cells and kill via perforin/granzyme-mediated apoptosis, with possible antibody-mediated ADCC/CDC contributing.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Multi-epitope peptides presented on MHC class I and II
trial_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06639074
disease_id_num_tar_ref
325
drug_id_num_tar_ref
927