gene_symbol
CD70
hgnc_id
HGNC:11937
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD70 IgG1 binds CD70 and engages Fc-mediated effector functions (ADCC by NK cells, CDC, and ADCP), leading to killing of CD70-expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Also known as TNFSF7; ligand for CD27
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06384261
disease_id_num_tar_ref
3855
drug_id_num_tar_ref
10404