gene_symbol
ITGAL
hgnc_id
HGNC:6148
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ALG antibodies bind CD11a on T cells and induce complement-dependent lysis and Fc receptor–mediated clearance (ADCC/phagocytosis), depleting the target-expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
polyclonal preparation; representative target
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06695741
disease_id_num_tar_ref
3859
drug_id_num_tar_ref
10417