gene_symbol
CCL22
hgnc_id
HGNC:10621
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
CCL22 engages CCR4 on the CAR T cells to enhance trafficking; killing occurs only when the CAR binds CD30 on target cells (perforin/granzyme cytolysis), not via CCL22.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CCR4 ligand (MDC); mediates trafficking/homing
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06090864
disease_id_num_tar_ref
328
drug_id_num_tar_ref
933