gene_symbol
CD28
hgnc_id
HGNC:1653
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-thymocyte globulin binds CD28 on T cells and triggers complement-dependent lysis and Fc receptor–mediated ADCC/phagocytosis, depleting the bound cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
costimulatory receptor
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06075706
disease_id_num_tar_ref
3897
drug_id_num_tar_ref
10512