gene_symbol
HLA-DRA
hgnc_id
HGNC:4947
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATG antibodies can bind HLA-DR on leukocytes and induce complement-dependent lysis and Fc-mediated ADCC/phagocytosis, depleting HLA-DR–expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
MHC class II
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06075706
disease_id_num_tar_ref
3897
drug_id_num_tar_ref
10512