gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR engagement activates T-cell cytotoxicity, leading to perforin/granzyme release (and death receptor signaling) that kills antigen-expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Target antigen for CAR-T in this ITP study not provided
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06352281
disease_id_num_tar_ref
3921
drug_id_num_tar_ref
10589