gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells bind the target antigen via the CAR and directly lyse antigen-expressing cells through perforin/granzyme release and death receptor (e.g., Fas/FasL) pathways.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Long-term follow-up of multiple CAR T-cell products; specific antigen varies by parent trial (e.g., CD19, BCMA, CD22, etc.). CARs recognize cell-surface antigens in an MHC-independent manner.
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05713214
disease_id_num_tar_ref
3931
drug_id_num_tar_ref
10619