gene_symbol
TNFRSF13C
hgnc_id
HGNC:17755
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells recognize BAFF-R via the CAR, become activated, and directly kill BAFF-R–expressing cells through perforin/granzyme-mediated cytolysis (and Fas–FasL pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
BAFF-axis receptor
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06279923
disease_id_num_tar_ref
3936
drug_id_num_tar_ref
10633