gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells bind CD19 via the CAR, activate, and directly lyse target cells through perforin/granzyme-mediated cytotoxicity (and Fas–FasL apoptosis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen; dual-target CAR recognizes CD19 or CD22
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06927466
disease_id_num_tar_ref
3952
drug_id_num_tar_ref
10671