gene_symbol
TNFRSF13C
hgnc_id
HGNC:17755
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Ianalumab is an anti–BAFF-R IgG1 that opsonizes BAFF-R+ B cells and recruits FcγR-expressing effector cells to mediate ADCC (and possibly complement-mediated lysis), depleting the target cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
TNF receptor superfamily member 13C; B-cell surface receptor
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05985915
disease_id_num_tar_ref
3958
drug_id_num_tar_ref
10688