gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
DC vaccine primes EBV/LMP2A-specific CD8+ T cells that recognize LMP2A peptides on MHC I of EBV-positive tumor cells and kill them via perforin/granzyme (and Fas–FasL) cytotoxicity, driven by a Th1/IFN-γ response.
enzyme_product
Off
epitope
On
variant
Off
isoform
On
hla_specific
On
gated
Off
other_modifier
EBV latency II/III antigen; presented via MHC I/II by autologous DCs
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06097793
disease_id_num_tar_ref
3961
drug_id_num_tar_ref
10694