gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
DC vaccine presents EBV antigens to prime EBV-specific CD8+ T cells; CTLs recognize LMP2B-derived peptides on MHC I of EBV+ cells and kill them via perforin/granzyme-mediated cytolysis (Th1/IFN-γ biased).
enzyme_product
Off
epitope
On
variant
Off
isoform
On
hla_specific
On
gated
Off
other_modifier
EBV latency II/III antigen; presented via MHC I/II by autologous DCs
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06097793
disease_id_num_tar_ref
3961
drug_id_num_tar_ref
10694