gene_symbol
KIT
hgnc_id
HGNC:6342
binding_type
other
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATP-competitive inhibition of KIT blocks autophosphorylation and downstream MAPK/PI3K–AKT survival signaling in KIT-dependent cells, causing growth arrest and apoptosis.
enzyme_product
On
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05816785
disease_id_num_tar_ref
3975
drug_id_num_tar_ref
10733