gene_symbol
CD70
hgnc_id
HGNC:11937
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-NKT cells recognize CD70 and kill target cells via MHC-independent perforin/granzyme-mediated cytolysis, with supportive pro-inflammatory cytokine effects.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface antigen; ligand for CD27
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06394622
disease_id_num_tar_ref
3988
drug_id_num_tar_ref
10762