gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD19-directed CAR NK cells recognize CD19 on target cells and directly kill them via NK degranulation (perforin/granzyme-mediated lysis) and apoptotic pathways.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CAR-mediated recognition; HLA-independent
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06518668
disease_id_num_tar_ref
346
drug_id_num_tar_ref
992