gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Glofitamab binds CD3 on T cells to activate and redirect them to kill CD20+ B cells; CD3+ cells are engaged, not targeted for killing.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell engaging arm (one CD3-binding arm)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05896163
disease_id_num_tar_ref
4051
drug_id_num_tar_ref
10920