gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Rituximab binds CD20 on B cells and induces killing via Fc-mediated ADCC (e.g., NK cells), complement-dependent cytotoxicity (CDC), and can directly trigger apoptosis.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Type I anti-CD20 antibody; binds epitope in the large extracellular loop of CD20
trial_id_tar_ref
drug_id_tar_ref
nct_id_tar_ref
NCT06468943
disease_id_num_tar_ref
4072
drug_id_num_tar_ref
10992