gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The vaccine induces neoantigen-specific CD8+ T cells that recognize the neoantigen peptide–MHC I complexes on tumor cells and kill them via perforin/granzyme-mediated apoptosis (and Fas–FasL pathways).
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Presented on HLA class I (e.g., HLA-A/B/C) by APCs and tumor cells; recognized by CD8+ T-cell receptors to mediate cytotoxicity.
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06026774
disease_id_num_tar_ref
4087
drug_id_num_tar_ref
11027