gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The vaccine primes endogenous neoantigen-specific T cells; activated CTLs (and sometimes cytotoxic CD4+ T cells) recognize the neoantigen peptide–MHC on tumor cells and kill them via perforin/granzyme and/or Fas–FasL pathways.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Presented on HLA class II (e.g., HLA-DR/DP/DQ) by antigen-presenting cells; recognized by CD4+ T-cell receptors to provide helper function.
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06026774
disease_id_num_tar_ref
4087
drug_id_num_tar_ref
11027