gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The antibody binds GD2 on target cells and engages effector functions via its Fc: NK cell/macrophage FcγR-mediated ADCC and complement-dependent cytotoxicity (C1q→MAC), leading to lysis of GD2+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Glycolipid (non-protein) antigen highly expressed on neuroblastoma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06071897
disease_id_num_tar_ref
4096
drug_id_num_tar_ref
11047