gene_symbol
DLL3
hgnc_id
HGNC:2909
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-T cells recognize DLL3 via the CAR and, upon activation, kill DLL3-positive cells through perforin/granzyme-mediated cytolysis (with cytokine release).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface Notch ligand
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05680922
disease_id_num_tar_ref
4103
drug_id_num_tar_ref
11071