gene_symbol
CD38
hgnc_id
HGNC:1667
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds CD38 on target cells and elicits Fc-mediated immune effector killing (ADCC by NK cells, CDC, ADCP) and can directly induce apoptosis, leading to lysis of CD38+ cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Inhibits CD38 ectoenzyme (NADase) activity
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05889221
disease_id_num_tar_ref
4128
drug_id_num_tar_ref
11146