gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
HLA-restricted recognition of JCPyV VP2–derived peptides on MHC I by infused JCPyV-specific CD8+ T cells triggers cytotoxic killing via perforin/granzyme and Fas–FasL pathways.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Viral peptide presented by patient HLA (class I and/or II) on infected cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05541549
disease_id_num_tar_ref
4143
drug_id_num_tar_ref
11197