gene_symbol
TNFRSF4
hgnc_id
HGNC:11918
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
IgG1 anti-OX40 binds OX40 on activated T cells and engages Fc effector functions (primarily ADCC, with possible ADCP/CDC) to deplete OX40+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface co-stimulatory receptor on activated T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05724199
disease_id_num_tar_ref
4146
drug_id_num_tar_ref
11206