gene_symbol
CD274
hgnc_id
HGNC:17635
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Peptide vaccine primes PD-L1–specific CD8+ T cells that recognize PD-L1–derived epitopes on target cells and kill them via CTL-mediated lysis (perforin/granzyme).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
long-peptide vaccine-derived antigen; induces Th1/CD8+ T-cell responses
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05977907
disease_id_num_tar_ref
4155
drug_id_num_tar_ref
11225