gene_symbol
SELPLG
hgnc_id
HGNC:10722
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Agonist engagement of PSGL-1 on chronically activated effector/memory T cells triggers inhibitory signaling that induces activation-induced cell death (apoptosis) of the PSGL-1–expressing T cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
agonist (immune checkpoint)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05723692
disease_id_num_tar_ref
4157
drug_id_num_tar_ref
11226