gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-BCMA CAR-engineered NK cells bind BCMA on target cells, activate NK/CAR signaling, and kill through immune-synapse formation with perforin/granzyme-mediated cytolysis (and death-receptor pathways), inducing apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface TNF receptor superfamily member on malignant plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06045091
disease_id_num_tar_ref
4166
drug_id_num_tar_ref
11243