gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD19-directed CAR T cells bind CD19 on target cells, activate, and kill via perforin/granzyme-mediated cytolysis and apoptosis (e.g., Fas–FasL).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Native extracellular domain on B-lineage cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05667506
disease_id_num_tar_ref
4209
drug_id_num_tar_ref
11352