gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BCMA-specific CAR-T cells bind BCMA on target cells, activate, and kill them via perforin/granzyme-mediated cytolysis and death-receptor pathways (e.g., Fas).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface receptor on malignant plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05870917
disease_id_num_tar_ref
4222
drug_id_num_tar_ref
11397