gene_symbol
ULBP3
hgnc_id
HGNC:14895
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NKG2D CAR-engineered NK cells recognize ULBP3 on target cells, become activated, and kill via degranulation with perforin/granzymes leading to apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D ligand
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06379451
disease_id_num_tar_ref
373
drug_id_num_tar_ref
1053