gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR recognition of BCMA activates engineered T cells, which kill BCMA-expressing cells via perforin/granzyme-mediated cytotoxicity (and Fas–FasL pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Also known as CD269; membrane-bound target on plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06630104
disease_id_num_tar_ref
4260
drug_id_num_tar_ref
11519