gene_symbol
RAET1G
hgnc_id
HGNC:16795
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NKG2D-CAR NK cells bind ULBP5 on target cells, triggering NK activation and degranulation (perforin/granzyme) and death receptor pathways, leading to apoptosis of the target cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D ligand
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06379451
disease_id_num_tar_ref
373
drug_id_num_tar_ref
1053