gene_symbol
CD5
hgnc_id
HGNC:1685
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD5-specific CAR T cells bind CD5 and, upon CAR signaling, directly kill CD5+ cells via perforin/granzyme-mediated cytotoxicity (and Fas/FasL pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface glycoprotein on T cells (and some B cells)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06633354
disease_id_num_tar_ref
4280
drug_id_num_tar_ref
11568