gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti‑CD19 CAR T cells bind CD19 on target cells, form an immune synapse, and induce death via perforin/granzyme release (and Fas/FasL signaling) following CAR activation.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
4-1BB costimulatory CAR; targets extracellular CD19 on B cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05672173
disease_id_num_tar_ref
4281
drug_id_num_tar_ref
11569