gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Etentamig engages CD3 to activate T cells, which then kill BCMA+ plasma cells; CD3+ T cells themselves are not targeted for killing.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Low-activating CD3 engagement to limit cytokine release
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06158854
disease_id_num_tar_ref
377
drug_id_num_tar_ref
1062