gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The mRNA vaccine primes HBV-specific CD8+ T cells that recognize HBV peptides on MHC I of target cells and kill them via perforin/granzyme; vaccine-induced antibodies may also mediate ADCC/complement.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
HBV protein antigens encoded by the mRNA and presented via MHC I/II; exact antigen(s) not specified
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05738447
disease_id_num_tar_ref
4316
drug_id_num_tar_ref
11680