gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-T cells bind CD19 via the CAR, become activated, and kill CD19+ cells through perforin/granzyme release and death receptor–mediated apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface B-cell antigen (pre-B to memory) targeted by CAR
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06285279
disease_id_num_tar_ref
4340
drug_id_num_tar_ref
11754