gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATLG antibodies bind CD3ε on T cells and deplete them via complement-dependent cytotoxicity and Fc-mediated ADCC; binding can also induce apoptosis.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CD3 complex subunit
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06525519
disease_id_num_tar_ref
4359
drug_id_num_tar_ref
11801