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gene_symbol
TRAC
hgnc_id
HGNC:12029
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATLG antibodies bind TCRα/TCR complex on T cells and induce complement-dependent cytotoxicity and Fc-mediated ADCC, leading to lysis and apoptosis of the T cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
component of TCR α/β complex
trial_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06525519
disease_id_num_tar_ref
4359
drug_id_num_tar_ref
11801