gene_symbol
RAET1E
hgnc_id
HGNC:16793
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
An NKG2D-based chimeric receptor on the engineered T cells binds ULBP4 (RAET1E), activating the T cells to degranulate and kill the ligand-expressing cell via perforin/granzyme-mediated cytotoxicity.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D ligand; stress-induced
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06568328
disease_id_num_tar_ref
4370
drug_id_num_tar_ref
11830